List of Research Titles

Advanced Human Support Technologies

Advanced Environmental Monitoring and Control

Akse, Microgravity Compatible Reagentless Instrumentation for Detection of Dissolved Organic Acids and Alcohols in Potable Water
Chutjian, Miniature Quadrapole Mass Spectrometer
Collins , Mesoscopic Instrumentation Minature FTIR for Environmental Monitoring and Chemical Analysis
Devereaux, Wireless Augmented Reality Prototype
Forouhar, Tunable Diode Lasers
Grannan, Micro-Scale Fluidic Technologies for AEMC
Grimes, In Situ, Remote Chemical Sensors Based On Thin Magnetic Films
Hines, Advanced Technology Development - Biosensors
Hodko, A New Reagentless Carbon Analyzer for Water Quality Monitoring in Space
Hoenk, SAW-Based Microhygrometer
Kounaves, Multisensor Array for Monitoring Water Quality on Spacecraft and Planetary Habitats
Lambert, Non-Invasive Monitoring of Physiological Analytes
Leleux, Novel Laser-Based Gas Sensors for Trace Gas Detection in a Spacecraft Habitat
Ligler, Multianalyte Biosensor with Chips for Human and Environmental Monitoring
McFeters, Rapid Bacterial Testing for Spacecraft Water
Miller , Development of a Tunable Diode Laser/Cavity Ring- Down Sensor for Monitoring Spacecraft Air Quality
Nealson, UV Microbial Detection and Sterilization
Paloski, Multianalyte Biosensor with Chips for Human and Environmental Monitoring
Porter, Miniaturized Liquid Chromatography
Ryan, Electronic Nose Re-Flight
Sayler , Towards Intelligent Distributed Bioluminescence Detection of Biological Contamination and Stressors
Simpson, Bioluminescent Bioreporter Integrated Circuits for Monitoring Spacecraft Environments
Stahl, DNA Microchip-Based Microbial Monitoring
Tittel, Laser Based Absorption Sensors for Trace Gas Monitoring in Spacecraft Environment
Zee, Advanced System Modeling and Control of Bioregenerative Life Support

Advanced Extravehicular Activity

Cadogan, Self-Sealing Bladder for Use In Pressurized Inflatable Structures
Koscheyev, An Innovative Physiologically Based Advanced Liquid Cooling/Warming Garment for Routine and Emergency EVA
Tourbier, Physiological Effects of a Mechanical Counter Pressure Suit

Advanced Life Support

Barta, Biomass Production - Plant Cultivation, Solid Substrates, Large-Scale Integrated Testing
Bonsai, Germplasm Development and Improvements
Both, Crop Modeling for Multiple Crop Production and Control for Advanced Life Support Systems
Both, Systems Studies at NJ-NSCORT
Both, Top Level Modeling of an Advanced Life Support System Using an Object Oriented Approach
Brasseaux, Air Revitalization Systems Development and Testing
Brinker, Biomimetic Self-Assembly of Hardened (Nacre-like) Nanocomposite Coatings for TransHab
Bugbee, Crop Optimization and Failure Analysis for Advanced Life Support
Cavazzoni, Plant Growth Chamber Experiments with Soybean and White Potato
Christodoulatos, Biodegradation and Nutrient Recovery of Inedible Plant Biomass for Advanced Life Support Systems
Christodoulatos, Biological Grey Water Treatment for Long Duration Space Missions
Cook, Evaluation of Constructed Microbial Communities as Inocula for Biological Life Support Systems
Cowan, In Situ Resource Utilization of Martian Regolith with Plant Compost from Crop Production
Cowan, Biological Treatment of Solid Waste: Composting, Biofiltration of Compost Offgas, and Nutrient Recovery from Compost
Crawford, ALS Power Reduction
Cuello , Hybrid Solar and Artificial Lighting for Space Life Support
Drew, Plant Growth and Metabolism at Sub-Ambient Atmospheric Pressures
Drysdale, Numerical Assessments of Life Support Options for Long Duration Space Missions
Ewert, Heat Pump Technology Development
Finn, Regenerable Incinerator Exhaust Purification and Trace Contaminant Control System
Finn, Advanced Life Support Power Reduction
Finn, CO2 Compressor
Finn, ISRU Technologies for Mars Life Support
Fisher, Reactive Carbon from Life Support Waste for Flue Gas Cleanup
Fisher, Waste Reclamation Process Development for Advanced Life Support
Flynn, The Development of a Solid Waste Treatment Technology for the Near Term Human Exploration of Mars
Flynn, VPCAR Water Processor
Franklin, Monitoring Spatial and Temporal Changes in Pathogen Invasibility of Microbial Communities in Hydroponically Grown Wheat
Frantz , Using CO2 Gas Exchange to Determine the Factors Controlling Respiration and Carbon Use Efficiency in Crop Plants
Fricker, Cryongenic Portable CO2 Removal System
Garland, Microbial Ecology
Giacomelli, Nutrient Delivery Systems for Salad Machine Crops
Giacomelli, Development of Chambers for Monitoring Canopy Gas Exchange
Gianfagna, Regulation of ADP- Glucose Pyrophosphorylase Subunit Expression -A Key Enzyme for Starch Biosynthesis in Plants
Goins, Performance of Salad-Type Plants Grown under Narrow Spectrum Light-Emitting Diodes (LEDs) in a Controlled Environment
Graf, Air Revitalization Systems Development and Testing
Hartman, Identification and Quantification of Volatile Organic Emissions from Living Tomato and Soybean Plants, Solid Waste Composter and Food
Hill, Food Technology and Utilization
Hunter, Cost Optimization of Food Preparation for Lunar and Planetary CELSS Stations
Johnson , Genetic and Environmental Influences on the Nutritive Value of Spinach, Spinacia oleracea, for Humans
Jones, Controls & Faults
Kokini, Development of Baked Products from a Space-Age Wheat Variety
Korfiatis, Investigation of Ambient Pressure, Non-Thermal Diffuse Plasmas for Destruction of Airborne Environmental Contaminants in ALS
Lee, Development of Extrusion Processes and Food Products to Be Used in an ALSS
Lee, Quality Evaluation of ALS Hydroponic Tomatoes for Their Suitability for Fresh Consumption and Processing
Levine, Development of a Microgravity-Rated Hydroponic Plant Culture Apparatus
Little, Automation of Plant Chambers
Lueptow, Rotation Membrane Water Purfication for Long-Term Human Presence in Space
MacKnight, Biological Wastewater Processor Experiment Definition
Mackowiak, The Efficacy of Plant Residue Degradation Products on Nutrient Bioavailability in Regenerative Life Support Systems
Mancinelli, Control Systems Integration in Closed Ecological Systems Using Denitrification as a Model
Mathieu , An Early Fault Detection System for Hydroponic Crop Production: Computer Simulation of Water and Nutrient Uptake
McGilloway, Kinetics of Nitrification by Isotope Dilution in Growth of Wheat Using Zeoponics
Ming, Zeoponic Plant Growth Substrates for Space Applications
Mortley, Crop Production and Environmental Systems
Overland , Development of 3T Control System for Advanced Life Support Applications
Pickering, Immobilized Microbe Microgravity Water Processing System (IMMWPS)
Russo, Malleable Human-Machine Interfaces
Schuerger, Use of Induced-Fluorescence Imaging and Green Fluorescent Proteins to Monitor the Health of Terrestrial Plants under Simulated Martian Environments
Strayer, Resource Recovery (Solid Waste Processing)
Strayer, Development of an Integrated System for Processing and Stabilization of Human Solid Wastes and Inedible Plant Biomass for Advanced Life Support Systems
Trachtenberg, Enzyme-Based Carbon Dioxide Capture and Removal
Tri, Advanced Life Support Systems Integration Test Bed (BIO-Plex)
Trotman, Investigation of Biological Approaches to Solid Waste Management and Resource Recycling
Vaccari, Global Modeling of an Integrated Life Support System
Wheeler, Candidate Crop Testing for Advanced Life Support

Behavior and Performance

Stone, Human Visual Self-Motion and Depth Estimation From Optic Flow in 1G

Physical/Chemical Regeneration

Atwater, Microgravity and Hypogravity Compatible Methods for Resource Recovery from Solid Wastes by Magnetically Assisted Gasification (MAG)
Savage, Size Reduction of Solid Wastes as a Pre-processing Stage for Biological, Physical, and Chemeical Processes

Space Human Factors Engineering

Akin, Development and Testing of a Mechanical Counterpressure Space Suit Glove
Caldwell, JSC MCC Center, Telex Multiplexer
Ellis, Studies of the Perceptual Stability and Position of Virtual Objects
Haney, Application of the FRANCIE Framework and Methodology to Assessing Human Reliability and Enhancing Human Performance in Aerospace Maintenance, Safety, and Crew Operations
Jung, Dynamic Human-Centered Interfaces: Monitoring Attentional Processes in Control of Critical Systems During Long and Ultra-Long Duration Human Space Missions
Kaiser, Assessing and Optimizing the Perceptual Utility of Immersive Display Media
Maida, Improving Human Task Performance with Luminance Images and Dynamic Overlays
Maida, An EVA Suit Fatigue, Strength, and Reach Model
Metaxas, Coupling Computer and Astronaut Performance for Muilti-Person Modeling and Analysis
Neumann, Augmented Reality for Space Flight
Newman , Quantifying Astronaut Tasks: Robotic Technology and Future Space Suit Development
Newman , Microgravity Investigation and Crew Reactions in 0-G (MICR0-G)
Oman, Advanced Displays and Controls for 6 DOF Orientation and Navigation in Virtual Microgravity
Parasuraman, Human Biology-Based Adaptive Systems in Support of Space Exploration
Raj, Haptic Interfaces to Augment Human/Machine Interaction in Space Activities
Shastri, Teleoperation of Life-Science Experiments with Telecommunication Time Delay
Stone, High-Resolution Video-Based Eye-Tracker Technology for Aerospace Applications
Walker , Manipulation and Contact Sensing via Trunks, Tentacles, and Whiskers
Watson, Optimized Visual Communication Systems
Woods, Orientation for Intervention: Supporting Mission Awareness in Space Operations
Zamorano, The Development and Human Factors Analysis of Advanced 3D-Visualization for Telepresence

Biomedical Research and Countermeasures

Behavior and Performance

Black , Otolith and Vertical Canal Contributions to Dynamic Postural Control
Bloomberg, Promoting Sensorimotor Response Generalizability: A Countermeasure to Mitigate Locomotor Dysfunction after Long- Duration Spaceflight
Brown, On-Line Analysis of Physiologic and Neurobehavioral Variables During Long-Duration Space Missions
Czeisler, Sleep-Wake Actigraphy Monitoring During Spaceflight
Czeisler, Circadian Entrainment, Sleep-Wake Regulation and Neurobehavioral Performance during Extended Duration Space Flight
Dijk, Acute Total & Chronic Partial Sleep Deprivation: Effects on Neurobehavioral Function, Waking EEG and Renin-Angiotensin System
Dijk, Quantitative EEG Monitoring of Vigilance: Effects of Sleep Deprivation, Circadian Phase and Sympathetic Activation
Eckstein, Quantitative Modeling of Human Saccadic Targeting During Visual Search
Gevins , Physiological Monitoring of Mental Workload
Harm, Virtual Reality Training: "Cybersickness" and Effects on Sensorimotor Functions
Helmreich, Cultural and Personality Determinants of Performance and Error Management
Kanas, Crew Member and Crew-Ground Interactions During International Space Station Missions
Lackner , Slow Rotation Room
Lackner , Adaptation in Artificial Gravity Environments
Lackner , Motor Adaptation to Coriolis and Contact Forces
Monk, Sleeping Short
Monk, Performance and Sleep Consequences of Repeated Phase Shifts within Appendix K Guidelines
Mullington, Sustained Partial Sleep Deprivation: Effects on Immune Modulation and Growth Factors
Oman, Visual Orientation in Unfamiliar Gravito-Inertial Environments
Oman, Human Orientation and Sensory-Motor Coordination in Prolonged Weightlessness (ISS HRF Expt. E085)
Paloski, Age Associated Differences in Postural Equilibrium Control: Implications for Space Flight
Staderman, Shared Augmented-Reality for Communication across Environments
Van Dongen, Predicting Vulnerability to Performance Impairment from Sleep Loss
Verghese, Processing Motion Signals in Complex Environments
Young, PI-in-a-Box

Bioethics

Brody, Protecting Scientific Integrity Through Disclosures of Conflicts of Interest

Biomedical Countermeasures

Whitson, Renal Stone Risk During Space Flight: Assessment and Countermeasure Validation

Environmental Health

Butler, Effects of Circadian Rhythms on Decompression Outcome
Pierson, A Comprehensive Characterization of Microorganisms and Allergens in Spacecraft Environment
Pilmanis, Staged Decompression to a 3.5 PSI EVA Suit Using an Argon-Oxygen (ARGOX) Breathing Mixture
Schweickart, Effects of Microgravity on Microbial Physiology
West, The Effects of EVA and Long-Term Exposure to Microgravity on Pulmonary Function

Operational and Clinical Research

Alfrey, Neocytolysis: Mechanisms and Limitations
Amidon, Impact of Microgravity on Drug and Nutrient Absorption
Barrett , Space Flight-Induced Reactivation of Latent Epstein-Barr Virus
Cavanagh , Bone Strain During OG Excercise
Charles, Jr., Compact, High Precision, Multiple Projection DEXA Scanner
Cohen, Non-Invasive Assessment of Susceptibility to Ventricular Arrythmias During Simulated Microgravity
Cohen, Instrumentation for Non-Invasive Assessment of Cardiovascular Regulation
Czeisler, Clinical Trial of the Efficacy of Melatonin as a Countermeasure for Entrainment to the Sleep/Wake Schedules Required During Shuttle Missions
Czeisler, Clinical Trial of Melatonin as Hypnotic for Neurolab Crew
Dinges, Countermeasures to Neurobehavioral Deficits from Cumulative Partial Sleep Deprivation During Space Flight
Dunn, Optical Biosensors for In-Flight Measurement of Hormone Levels
Fox, DNA Probe Design for Preflight and Inflight Microbial Monitoring
Good, The Role of Intracranial Pressure in Space Adaptation Syndrome
Kline- Schoder, Feedforward Active Noise Reduction Headphones for Otoacoustic Hearing Assessment of Space Station Crews
LeBlanc, Noninvasive Monitoring of Bone Resorption and Sweat Calcium Using Skin Patches
McGinnis, Space Flight Effects on Fungal Growth, Metabolism, and Sensitivity to Antifungal Drugs
Pawelczyk, Facilitated Blood Pressure Control by Skin Cooling: Autonomic Mechanisms
Pierson, Automated Use of DNA Probes for Rapid Detection of Bacteria in Water
Pierson, Incidence of Latent Virus Shedding During Space Flight
Potember, Miniature Time of Flight Mass Spectrometer
Schoeller, Measurement of Body Composition For Nutrition Assessment in Microgravity
Seely, Dual-Energy X-Ray System for Bone Mineral Densitometry and Diagnostic Radiography
Shackelford, Prevention of Bed Rest Osteoporosis: Resistive Exercise
Sheehan, Visual Anatomic Guidance to Facilitate Ultrasound Image Acquisition
Stein, Protein and Energy Status During Long-Term Space Flight
Thomas , Digital Echocardiography in Manned Space Flight: Remote Diagnosis and Quantitative Analysis
Walsworth, Biomedical Investigations with Laser- Polarized Noble Gas Magnetic Resonance
Yelle, Individual Susceptibility to Post-Spaceflight Orthostatic Intolerance: Contributions of Gender-Related and Microgravity-Related Factors

Physiology

Albert, Hyperpolarized 129Xe MRI of the Brain, Lungs and Plants
Blomqvist, Integration of Neural Cardiovascular Control in Space
Bloomfield, Bone Blood Flow and Simulated Microgravity
Bungo, Human Cardiovascular Performance in the Space Flight Environment
Butel, Immune Function and Reactivation of Latent Viruses
Cavanagh , Foot Reaction Forces During Space Flight
Clement, Eye Movements and Motion Perception Induced by Off-Vertical Axis Rotation (OVAR) at Small Angles of Tilt After Spaceflight
Cohen, Cardiovascular Deconditioning in Humans: Alteration in Cardiovascular Regulation and Function During Simulated Microgravity
Cohen, Adaptation to Linear Acceleration in Space (Atlas) - Spatial Orientation of Vestibulo-Occular Reflex and of Velocity Storage
Collinsworth, Cytoskeletal Contributions to Changes in Elasticity of Mammalian Myocytes after Cyclilc Mechanical Loading
Convertino, Investigations of Mechanisms Associated with Blood Volume and Pressure Regulation
Crandall, Microcirculatory Adjustments to Simulated Microgravity Exposure in Humans
Cubano, Determining Cellular Responsiveness to Low Gravity Environments
Dyck, Pyruvate Supplementation on Muscle Metabolism
Eckberg , Autonomic Neuroplasticity in Weightlessness
Epstein , Molecular Signaling in Muscle Plasticity
Ferrando , Protein Turnover During Space Flight
Ferrando , Nutritional Interventions to Improve Muscle Protein Metabolism During Stress
Fitts, Effect of Prolonged Spaceflight on Human Skeletal Muscle
Fitts, Limb Muscle Function with Unloading and Countermeasures
Gestl, Transgenic Zebrafish as an Indicator of Mutagenic Risk
Goldberg, Effect of Unloading on Protein Content in Skeletal Muscle: Regulation of the Ubiquitin-Proteasome System
Gosselink, Neuromuscular and Endocrine Factors in Weightlessness-Induced Atrophy
Greenleaf, Exercise Training on Short- and Long- Arm Centrifuges
Hamilton , Activity Dependent Signal Transduction in Skeletal Muscle
Hargens, Exercise Within LBNP to Produce Artificial Gravity
Holmes, The Role of the Cerebellum in Cardiovascular Responses to Changes in Gravity
Kamm, Computational Models of the Cardiovascular System and Its Response to Microgravity
Kerman, Vestibular Influences on Different Outflow Limbs of the Sympathetic Nervous System
Lang, Sub-Regional Assessment of Bone Loss in the Axial Skeleton in Long-Term Spaceflight
Levine, Cardiac Atrophy and Diastolic Dysfunction During and After Long Duration Spaceflight: Functional Consequences for Orthostatic Intolerance and Risk of Cardiac Arrhythmias
Looft- Wilson, Microvascular Alterations after Simulated Microgravity
MacLean, Bed Rest and Neurovascular Function
Martinez , Healing Response of Injured Rodent Knee Ligaments to Hindlimb Unweighting and the Therapeutic Efficacy of Growth Hormone
Merfeld, Influence of Sensory Integration on the Neural Processing of Gravito-Inertial Cues
Moore, Validation of Centrifugation as a Countermeasure for Otolith Deconditioning During Space Flight
Mosier, Motoneuron Influences on Muscle Atrophy in Simulated Microgravity
Muenter, Sleep Restriction and Mechanisms of Orthostatic Tolerance
Mullen, Visual-and Vestibular-Autonomic Influence on Short-term Cardiovascular Regulatory Mechanisms
OMalley, Novel Receptor-Based Countermeasures to Microgravity-Induced Bone Loss
Paloski, Spatial Reorientation of Sensorimotor Balance Control in Altered Gravity
Pierson, Flight-Induced Changes in Immune Defenses
Purdy, Mechanisms of Microgravity Effect on Vascular Function
Putcha, Gastrointestinal Function During Extended Duration Space Flights
Ray, Effect of Head Movement on Sympathetic Nerve Activity in Humans
Reschke, Visual-Vestibular Mediated Gaze and Head-Eye Control in Altered Gravitoinertial Environments
Robertson, Autonomic Neurophysiology in Microgravity
Rosenthal, Molecular Mechanisms Regulating Muscle Fiber Composition Under Microgravity
Rubin, Optimization of a Biomechanical Countermeasure for Disuse Osteoporosis
Ruff, Skeletal Structural Consequences of Reduced Gravity Environments
Ryder, PTH Modulates the Response of Osteoblast- like Cells to Mechanical Simulation
Sandoval, The Effects of Gender on Sympathetic Response to Hypoxic Exercise
Schlegel, Vestibular-Autonomic Interactions During and After Prolonged Gravitational Changes
Schneider, Cardiac Atrophy
Schultheis, The Effects of Partial Mechanical Loading and Ibandronate on Skeletal Tissues in the Adult Rat Hindquarter Suspension Model of Microgravity
Schwartz, Role of Growth Hormone Secretogoues and Exercise on Muscle Homeostasis Under Microgravity
Schwartz, GH/IGF-I Transgene Expression on Muscle Homeostasis
Shearer, Space Flight Immunodeficiency
Shelhamer, Context-Specific Adaptation of Gravity-Dependent Vestibular Reflex Responses (NSBRI Vestibular Project 1)
Shoukas, Rodent Studies of Cardiovascular Deconditioning
Sinoway, Neurovascular Response to Bedrest
Smith, Calcium Kinetics During Space Flight
Smith, Vestibular Modulation of Autonomic Responses to Orthostasis
Smith, Effects of Hind Limb Suspension on Local Inflammation and Wound Healing in a Murine Model
Smith, Iron Absorption and Metabolism During Space Flight
Stein, Glucose Kinetics and Muscle Atrophy
Stoecker, Role of Vitamin E in Preventing Oxidative Damage to Bone in Near Weightlessness
Tesch, Effects of Resistance Training, Using Fly-Wheel Technology, on Size and Function of Unloaded Skeletal Muscle
Wall, Advanced Techniques for Assessment of Postural and Locomotor Ataxia, Spatial Orientation and Gaze Stability
Warren , Fatness, Food Intake and Hypergravity: Mechanisms of Regulation
West, Sleep and Respiration in Microgravity
Whalen, Non-Invasive Investigation of Bone Adaptation in Humans to Cumulative Daily Mechanical Loading
Williams, Renal and Cardio-Endocrine Responses in Humans to Simulated Microgravity
Williams, Human Studies Core
Wootten , Short-term Time Course Skeletal Responses to High Intensity Physical Activity
Yelle, Characterization of Autonomic Function, Sodium Handling, and Nitric Oxide Physiology in Astronauts and Patients Known to Be Susceptible to Orthostatic Intolerance

Radiation Health

Badhwar, Organ Dose Measurement Using the Phantom Torso
Barcellos-Hoff, HZE and Proton Induced Microenvironments
Barcellos-Hoff, Interaction Between Tissue and Cellular Stress Response Following Charged Particle Exposure
Bedford, HZE Radiation-Induced Chromosome Instability
Blakely, Lens Epithelium and Proton-Induced Cataractogenesis
Borak, Microdosimetric Studies
Brooks, In Vivo Induction and Repair of Genomic Instability
Burns, Cancer Risk Mechanisms Following Repeated Exposure to High LET Radiation
Carnes , Radiation Risk Analysis: Model Issues and Interspecies Extrapolation
Chatterjee, Theoretical Modeling of DNA Damage and Cellular Responses
Chen, Roles of Human Recombination in Genome Instability
Cooper, DNA Repair and the Early Development of Chromosomal Changes (COOPER)
Dicello , Radiation Effects: Core Project
Evans, Induction of Genomic Instability in Human Lymphoblasts
Hall, High-Energy Ions and Genomic Instability
Hall, Individual Susceptibility to Radiation Effects
Huso, Chemoprevention of Radiation-Induced Neoplasms
Iliakis, Factors Modulating Radiation-Induced G-2 Delays
Kronenberg, Mutagenesis in Human Cells With Accelerated H and Fe Ions
Kronenberg, High-LET Radiation and Genomic Instability in Human Cells
Kronenberg, Mutagenesis and Chromosomal Alterations
Lowenstein, AGS Beam Time (HZE Particles)
Maurer, In-Situ Spectrometry of Neutrons
Meinhold, Operational Radiation Safety Program for Astronauts
Morgan, Mechanisms of High-LET Induced Genomic Instability
Murnane, Telomere Repair and Chromosome Instability After High-LET Particle Radiation
Rabin, Effects of Exposure to Heavy Particles
Setlow , Germ Cell Mutagenesis in Medaka Fish Following Exposure to Heavy, High Energy Cosmic Ray Nuclei
Sinden, Quantitation of Radiation-Induced Deletion and Recombination Events Associated with Repeated DNA Sequences
Tlsty, Mechanisms of Radiation-Induced Genomic Instability
Turner, NAG5-3888 Risk Management Strategies During Solar Particle Events on a Human Mission to Mars or the Moon
Ullrich, Genomic Instability in High-LET Carcinogenesis
Williams , Radiation-Induced Cytogenetic Damage as a Predictor of Cancer Risk for Protons and Fe Ions

Fundamental Biology

Advanced Technology Development

Daunert, Biomimetic Detection Schemes Based on a Microcentrifuge Platform

Cellular and Molecular Biology

Bada, Mars Organic Detector (MOD): Looking for Clues for Life and Evaluating the Water Inventory for In SItu Resource Utilization
Baird, Physiological Maturation of Regenerating Hair Cells
Bellen , Role of MATH1 in Development and Function of Proprioreceptors
Bendixen, Negative Regulation of Osteoclastogenesis by Estrogens via Direct Actions on Hematopoietic Cells
Braam, Molecular and Developmental Responses of Plants to Mechanical Stimuli
Brown, Changes in Gene Expression During Gravistimulation
Brown, Signal Transduction Pathways and Early Responses to Gravistimulation
Brown, Effects of Gravity on Metabolism
Brown, NSCORT. Calcium, Signaling and Gravity: An Integrated Molecular, Cellular and Physiological Approach to Plant Gravitational Biology
Brown, Changing Calcium Homeostasis in Transgenic Plants: A Reverse Genetics Approach
Brown, Isolation of a Novel Class of Mutants with Impaired Transduction of the Gravity Signal
Chapes, Bone Marrow Macrophage Differentiation in Space
Civitelli, Osteoblast Regulation by Mechanical Stimuli via Gap Junctions
Cosgrove, Gravity Effects on Seedling Morphogenesis
Cyr, Regenerating Protoplast as a Single-Cell Model System for Studying the Gravitropism in Plants
D'Alonzo, Transcriptional Regulation of Differentiating Osteoblasts
Demain, Effect of Growth and Starvation under Simulated Microgravity on Bacterial Stress and Secondary Metabolite Formation Responses Using Rotating Wall Bioreactors
Duke, Relationship of Morphogenesis and Mineralization to Gravitaxis in Spaceflown Algae
Durban, Gravity and the Regulation of a Central Growth Factor Pathway
Eward, Technologies for Assessing the Effects of Long-Term Space Habitation on Cellular Aging
Fedoroff, The Use of Arabidopsis Transposon Mutants in the Study of Gravitropism
Feeback, Mechanical Loading, Growth Factor Release and Regulation of Skeletal Muscle Mass: A Potential Site for the Application of Microgravity-Induced Muscle Atrophy Countermeasures
Feldman, Early Gravitropic Events in Roots of Arabidopsis: Ca2+ and H+ Fluxes in the Columella Cells
Ferl, Transgenic Plant Biomonitors of Space Flight Exposure
Fox, Effects of Gravity on Endothelial Cell Functions
Globus, Do Integrins Mediate the Skeletal Responses to Altered Loading in Vivo
Grinnell , Regulation of Vesicular Neurosecretion by Mechanical Stress on Integrins in Nerve Terminal Membranes
Gustin , Pressure-Sensing MAP Kinase Cascades in Yeast and Mammals
Hammond, Neurolab Reflight
Hasenstein, Application of Physical and Biological Techniques in the Study of the Gravisensing and Response System of Plants
Hashemi, The Interactive Coupling of Cytoskeleton and Signal Transduction Elements in Gravity Sensitivity of T-Cell Activation
Hughes-Fulford, Role of the Interlukin-2 Receptor in Signal Transduction and Gravisensing Threshold of T Lymphocytes STS-107 NAG2-1286
Ingber, Mechanotransduction through the Cytoskeleton
Jo, Molecular Basis of Mechano-Signal Transduction in Vascular Endothelial Cells
Kosik, A DNA Chip Approach to the Discovery of Gravity Response Genes in Brain and Muscle
Landis, The Effect of Hypergravity on Bone Cell Cultures
Lee, Sarcoglycans and Vascular Smooth Muscle Cell Mechanics
Lelkes, Altered Signal Transduction and Differential Gene Expression in PC12 Phochromocytoma Cells Cultured in "Simulated Microgravity"
Masson, Molecular Cloning and Characterization of the AGR1 Gene of Arabidopsis thaliana
Masson, Molecular Genetics of Root Thigmoresponsiveness in Arabidopsis thaliana
McIntire , Laminar Fluid Flow Effects on Mammalian Cell Protein Synthesis and Secretion
McKay, Mars Immunoassay Life Detection Instrument (MILDI)
McNeil , Cellular and Molecular Mechanisms Mediating Rapid Resealing of Gravity-Inducedplasma Membrane Distribution
Mikos, Mechanical Load Effects on Bone Formation
Mitsuo, Bone Matrix Changes During Skeletal Unloading and Reloading
Morre, A Graviresponsive Time-Keeping Protein of the Plant and Animal Cell Surface
Morrow, Effect of Simulated Microgravity on Activated T Cell Transcription
Muday, Fucus as a Model System to Study the Role of Auxin Transport and the Actin Cytoskeleton in Gravity Response
Nickerson, Effect of Simulated Microgravity on Gene Expression in the Enteric Pathogen Salmonella typhimurium
Niesel, Streptococcus pneumoniae Gene Expression and Virulence Potential in the Space Environment
Nowakowski, Murine Development: Cellular and Molecular Analysis
Pellis, Microgravity Induced Changes in Lymphocyte Movement Through Interstitium
Poovaiah , Calcium/Calmodulin-mediated Gravitropic Response in Plants
Reddy, Gravity-Induced Changes in Gene Expression in Arabidopsis
Rhoten, Calbindins and Apoptosis after Short-Term Space Flight
Roux, Cellular Bases of Light-Regulated Gravity Responses
Rowe, Use of GTP Transgenes to Assess Osteoprogenitor in Intact Bone (This Task began in FY 2001)
Sams, T Cell Activation and Signal Transduction in Simulated Microgravity
Staehelin, Integrated Analysis of Columella Cell Structure and Function
Sukharev, Mechanosensitive Channels in Bacteria: Functional Domains and Mechanisms of Gating
Triplett, Gravity Induced Changes in Gene Expression During Cotton Fiber Development (This Task Began in 2001)
Vandenburgh, Effect of Space Travel on Skeletal Myofibers
Vandenburgh, Growth Factors and Tension-Induced Skeletal Muscle Growth
Wang, Effects of Gravitational Forces of Cell Movement and Development
Wang, Microarray of Analysis of Microgravity-Dependent Gene Expressions in Normal Human
Wang, Cloning and Functional Characterization of Novel Genes Whose Expressions are Microgravity-Dependent in Normal Human Fibroblasts
Zygourakis, Microgravity Effects on Lymphocyte Adhesion and Motility

Developmental Biology

Baldwin, Neuro-Thyroid Interaction on Skeletal Isomyosin Expression in 0-G
Chapman, Microgravity Effects on Developing Vestibular Afferents
Conger, Gravitational Effects of Embryogenesis in Poaceae
Danilchik, How Do Cell-Division Planes Specify Regional Gene Expression Patterns in Early Embryos?
DeLuca, Effect of Microgravity on the Development of the Immune System
Doty, Skeletal Development in Embryonic Quail on the International Space Station
Fritzsch , The Development of Vestibular Connections in 1G and Hypergravity
Hoban-Higgins, Effects of Gravity on Insect Circadian Rhythmicity
Holbrook, Biomechanics of Arabidopsis thaliana Wavy Root Development
Jones, Vestibular Ontogeny, Adaptation and the Effects of Gravitational Loading in the Rat
Keshishian, Effects of Space Flight on Drosophila Neural Development
Klement, Pre-Metatarsal Differentiation and Mineralization
Kosik, Neuronal development under conditions of space flight
McCaffery, The Effect of Hypergravity on Retinoic Acid Signaling in the Developing Embryo
Moorman, Effects of Microgravity on Zebrafish Vestibular Development
Nowakowski, Reduced Gravity: Effects in the Developing Nervous System
Riley, Effects of Microgravity on Neuromuscular Development
Ronca, Hypergravity Effects on the Maternal-Fetal System
Roux, Early Development of Fern Gametophytes in Microgravity
Sack, Development of Gravity Sensitive Plant Cells (Ceratodon) in Microgravity
Sajdel-Sulkowska, The Effect of Hypergravity on Cell Adhesion Molecules in the Developing Central Nervous System
Schultz, Skeletal Muscle Growth and Repair During Microgravity
Walton, Effects of Microgravity on Postnatal Motor Development
Walton, Gravitation and Development of Motricity
Wolgemuth, Development and Function of the Mouse Vestibular System in the Absence of Gravity Perception

Evolutionary Biology

Bronner-Fraser, Evolution of the Neural Crest and Placodes
Davidson, Transcriptional Regulation and Evolution of Bilaterian Body Plans
Gerhart, Hemichordates and the Origin of Chordates
Holland, Evolution of the Neural Crest and Placodes
Janies, Large Data Set Analysis: Deuterostome Evolution NAG2-1399
Martindale, The Evolutionary Origin and Deployment of the Hox and ParaHox Genes in the Metazoa
Peterson, Transcriptional Regulation and Evolution of Bilaterian Body Plans
Rothenberg, Transcription Factor Evolution and Lymphocyte Origins
Shankland, Evolutionary Origin of Body Axis Segmentation in Annelids and Arthropods
Weisblat, Comparative Analyses of Segmentation During Embryogenesis, Post-Embryonic Growth and Regeneration among Annelids
Wheeler , Numerical and Computational Techniques in Phylogenetic Analysis NCC2-1169
Wray, Evolution of a Gene Regulatory System: Structural and Functional Analyses of Evolutionary Diversification of the Endo16 Promoter

Molecular Structures and Physical Interactions

Allen, The Cytoskeleton and Force Response Mechanisms

Organismal Biology

Balaban, Vestibulo-Autonomic Circuits
Beckingham, Gravitaxic Mutants and Mechanical Signaling in Drosophila
Bernstein, Role of Adrenergic Receptors in Adaptation to Microgravity: Gene Targeted Mice as a Model of Microgravity Research
Bikle, The Effect of Skeletal Unloading on Bone Formation
Booth, Signaling of Muscle Atrophy with Unloading
Brady, Space Flight, Stress, and Neuronal Plasticity
Cosgrove, Molecular Control of Cell Growth During Gravity Responses of Maize Seedlings
Delp, Adaptations of Visceral and Cerebral Resistance Arteries to Simulated Microgravity
Delp, Arterial Remodeling and Functional Adaptations Induced by Microgravity
Dickman, Development and Function of the Avian Otolith in Normal and Altered Gravity Environments
Dickman, Otolith-Canal Convergence in Vestibular Nuclei Neurons
Evans, Analysis of the Interaction of Environmental Signal Transduction Pathways Using Gravi-Compensation
Evans, The Regulation of Growth in the Distal Elongation Zone of Maize Roots
Ferl, Genetically Engineered Plant Biomonitors in Microgravity
Frangos , Microgravity In Vitro Model of Bone: Flow Effects
Fuller, CNS Control of Rhythms and Homeostasis During Space Flight
Gilroy, Gravitropism in Chara Rhizoids
Halloran, Space Flight and Bone Metabolism: Age Effects
Hasenstein, Analysis of the Gravisensing System in Chara
Highstein, Chronic Recording of Otolith Nerves in Microgravity
Hoffman, Hypergravity-Induced Modifications in Spatio-Temporal Coding among Utricular Primary Afferent Neurons
Hoffman, Embryonic Cell Migration and Metalloproteinase Activity Are Affected by Randomization of the Gravity Vector
Holstein, Nitric Oxide Signaling in Hypergravity- induced Neuronal Plasticity
Holstein, Anatomical Studies of Central Vestibular Adaptation
Lelkes, Effect of Spaceflight on Adrenal Medullary Function
Lewis, Lignification: A New Paradigm
Lomax, Interactions between Gravity and Light in Determining Plant Form: Analysis Using the lazy-2 Mutant of Tomato
Lysakowski, Ultrastructural, Neurochemical and Developmental Responses to Hypergravity
Musgrave , Microgravity Effects on Seed Development and Maturation
Pickard, Integration of Plant Responses to Mechanical, Thermal, Electrical, and Chemical Signals
Pyle, Bacterial Physiology and Virulence on Earth and in Microgravity
Ross, Multidisciplinary Studies of Synaptic Placticity in Space-Flown Rats
Rowe, Transgenic markers of bone cell lineage progression
Stutte, Photosynthesis and Metabolism of Super Dwarf Wheat in Microgravity
Stutte, Effect of Microgravity on Raphanus sativus L. in Microgravity
Tidball, Mechanical Signal Transduction in Countermeasures to Muscle Atrophy
Tischler, Influence of Unweighting on Insulin Signal Transduction in Muscle
Wade, Effect of Gravity on Energy Expenditure by Rats
Warchol, Immunological Influences on the Vestibular Sensory Organs
Wolverton, The Role of Electrical Events in Controlling Differential Elongation and Gravitropism in the DEZ

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